Sapienza University of Rome

Overview

The PhD in Molecular Medicine at Sapienza University of Rome is designed to cultivate skilled researchers who excel in cutting-edge biomedical research. This program emphasizes the translation of molecular and genetic discoveries into practical clinical applications, equipping students with the knowledge to address complex disease mechanisms, develop advanced diagnostics, and implement targeted therapeutic strategies.

What you'll study

The curriculum is research-driven, centered around an individual project under the guidance of faculty members, complemented by various academic and scientific training activities. Students will engage in laboratory and translational research, culminating in a thesis that reflects their findings and contributions to the field.

Current research themes include:

• Molecular and genetic mechanisms in brain tumors
• Molecular and genetic aspects of T-lymphocyte leukemia
• Drivers of solid tumors at the molecular and genetic levels
• Haematological malignancies and their molecular genetics
• Molecular factors involved in cardiomyopathies
• Epigenetic regulation in stem cells, both normal and neoplastic
• Metabolic reprogramming in cancer
• Signaling pathways affecting neuronal development and their pathological implications
• Molecular aspects of hereditary and familial cancers, including breast and ovarian cancer
• Genetic factors related to diabetes mellitus
• DNA damage response and associated syndromes
• Characterization of circulating tumor DNA (ctDNA) for diagnostic and prognostic purposes

Thesis requirement: Students must complete a PhD thesis based on their research project, followed by a final evaluation as per Sapienza’s PhD regulations.

Entry requirements

Admission is based on the evaluation of a submitted research proposal and an interview, with specific GRE/GMAT requirements not indicated. Prospective students should ensure they meet any additional academic prerequisites outlined by the university.

Career prospects