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Almost half of the world’s population is at risk of contracting dengue, chikungunya, yellow fever, and Zika viruses. These diseases are predominantly transmitted by the mosquito Aedes aegypti and disproportionately affect low- and middle-income countries. Dengue alone is estimated to cause around 390 million infections each year. We want to help change that. This Wellcome Trust-funded project aims to overcome a major bottleneck in the development of homing gene drive technology in Aedes aegypti…