Robert Gordon University

Overview

The PhD program in ATP-Binding Cassette Transporters in Obesity at Robert Gordon University offers a unique opportunity to explore the role of ABC transporters and lipid transport pathways in obesity. This research-focused degree aims to identify potential drug targets for managing long-term chronic conditions associated with obesity, combining advanced gene and protein expression profiling with relevant cell culture models.

What you'll study

Research-led PhD

• Develop a comprehensive research proposal that aligns with the theme of ABC transporters in obesity and their implications for chronic conditions.
• Manage progress through established milestones, including proposal development, research training, and formal reviews, leading to a final thesis submission.

Indicative work components

• Expression mapping: Profiling ABC drug and lipid transporter expression across tissues using a mouse model of diet-induced obesity.
• Validation: Confirming differential expression at both gene and protein levels for selected transporter targets.
• Tissue-relevant models: Utilizing tissue-specific cell culture systems to study transporter expression under controlled conditions.
• Data analysis: Integrating in vivo and in vitro findings to support target prioritization and research conclusions.

Topic flexibility

• Applicants are encouraged to propose specific research ideas, subject to supervisory approval.
• The University may provide additional self-funded topics within relevant Schools for consideration during project development.

Entry requirements

• A first or upper second class honours degree from a UK university, an overseas university, or an equivalent qualification, subject to approval by Robert Gordon University.
• Applicants with other qualifications may be assessed based on their merits, considering the nature and scope of the proposed research program.
• Typically, registration is for an MSc/PhD or MRes/PhD, with transfer to PhD contingent on satisfactory progress. Candidates holding a Master’s degree with a significant research component may qualify for direct PhD registration, pending an acceptable research proposal and evidence of research expertise.

Career prospects

Graduates of this program will be well-equipped for a range of career opportunities in academia, research institutions, and the pharmaceutical industry. The expertise gained in understanding obesity-related mechanisms and drug target identification positions them for roles in biomedical research, clinical development, and health policy. Additionally, this program fosters critical thinking and research skills that are valuable in various professional fields.