University of California

What you'll study

This master’s focuses on the scientific and methodological foundations required to design, run and interpret clinical research. Core subject areas typically include:

• Clinical research methods: protocol development, study design, clinical trial phases and participant recruitment strategies.
• Biostatistics and data analysis: statistical inference, regression modelling, survival analysis, and use of statistical software for clinical datasets.
• Epidemiology and outcomes research: observational study designs, causal inference, population health measures and health services research techniques.
• Medical physiology and disease mechanisms: systems-level understanding of pathophysiology relevant to clinical investigation.
• Pharmacology and therapeutics: principles of drug development, safety monitoring and pharmacokinetics/pharmacodynamics.
• Research ethics and regulation: informed consent, institutional review boards, Good Clinical Practice and regulatory requirements.
• Translational science and implementation: moving discoveries from bench to bedside, biomarkers, and strategies for integrating new interventions into practice.
• Practicum or capstone project: an applied research placement or thesis in collaboration with clinical departments, often involving patient‑centred studies, clinical trial work or secondary analysis of clinical data.

Teaching methods mix lectures and seminars with hands‑on workshops in statistics and trial management, supervised research, and placements within affiliated hospitals or research units. Electives allow specialisation in areas such as oncology, cardiovascular medicine, infectious disease or health services research.

Entry requirements

Applicants are expected to hold a recognised bachelor’s degree in a relevant discipline such as biology, biomedical sciences, nursing, pharmacy, public health or a related health science. Typical application elements include:

• A strong academic record demonstrating preparation for graduate‑level study in quantitative and biological subjects.
• Personal statement outlining research interests and career goals in clinical science or translational research.
• Letters of recommendation, preferably including at least one academic reference and one from a clinical or professional supervisor where applicable.
• Evidence of research experience, clinical exposure, or relevant professional experience is advantageous.
• Some campuses may request GRE scores, while others have an optional or waived GRE policy—check the specific campus admissions guidance.
• For applicants whose first language is not English, proof of English proficiency is required in line with University of California regulations.

Selection also considers fit with faculty research interests and the availability of suitable practicum or thesis supervision.

Career prospects

Graduates move into a range of roles across academic, clinical and industry settings. Common career pathways include:

• Clinical research coordinator or manager in academic medical centres and research hospitals.
• Clinical scientist or research associate in pharmaceutical, biotechnology or medical device companies.
• Regulatory affairs and clinical quality roles supporting trial compliance and submissions.
• Health data analyst or outcomes researcher in healthcare systems, insurers or public health agencies.
• Progression to doctoral research (PhD) in clinical, translational or biomedical sciences, or used as preparation for clinical professional programmes.

The University of California’s clinical and research networks provide opportunities for internships, collaborations with industry partners and exposure to multidisciplinary teams, which support transition into professional roles.

Why study at University of California

The University of California offers a research‑intensive environment with direct links to major teaching hospitals, specialised clinical research centres and cutting‑edge laboratories. Students benefit from interdisciplinary collaboration across medicine, public health, engineering and data science, plus access to experienced faculty actively engaged in clinical trials and translational projects.

Facilities include dedicated clinical research units, biostatistics and informatics support, and opportunities to contribute to ongoing patient‑centred studies. The UC system’s industry connections and regional healthcare networks also help students gain practical placements and build professional networks that support career development in clinical science and translational research.